Mr. T and Mr. B are mahjong buddies, admitted to Neuro-ICU with ischemic stroke. Hypothetically they have different arteries blocked due to embolism.

Mr. T who is right-handed has left middle cerebral artery affected. Mr. B who is also right-handed has the right anterior cerebral artery affected.

As an ICU nurse, you need to explain to the relatives of Mr. T and Mr. B about the disease and why they have different symptoms.

• Describe the blood supply of the brain.
• Based on your understanding of the physiology, assuming there is no collateral circulation, explain the difference in the presenting symptoms in Mr. T and Mr. B.